---
title: 'Four theses defended in Applied Physics'
url: 'https://sysbio.taltech.ee/news/220615-theses-applied-physics'
markdown: 'https://sysbio.taltech.ee/news/220615-theses-applied-physics.md'
date: '2022-06-15'
description: "Congratulations to four students from the Laboratory of Systems Biology who defended their theses in Applied Physics. Cärolin Grahv defended her bachelor's thesis, Deconvolution of three-dimensional epifluorescence microscopy images. Supervised by Marko Vendelin and Martin Laasmaa, her work evaluat…"
taxonomy:
  tag:
    - thesis
    - MSc
    - BSc
    - physics
    - 'fluorescence microscopy'
    - deconvolution
    - 'mathematical modeling'
    - cardiomyocytes
    - mitochondria
    - 'raster image correlation spectroscopy'
---

# Four theses defended in Applied Physics

Congratulations to four students from the Laboratory of Systems Biology who defended their theses in Applied Physics.

Cärolin Grahv defended her bachelor's thesis, *Deconvolution of three-dimensional epifluorescence microscopy images*. Supervised by Marko Vendelin and Martin Laasmaa, her work evaluated Richardson-Lucy deconvolution with total-variation regularization for three-dimensional epifluorescence images and established a measured point-spread function for the microscope.

Celica Krigul defended her bachelor's thesis, *Application of distribution-moment approximation to a cooperative muscle-force model*. Supervised by Marko Vendelin, her work applied a computationally efficient distribution-moment approximation to a model of cooperative cross-bridge activity in muscle contraction.

Otto Gustavson defended his bachelor's thesis, *Modelling of cardiomyocyte bioenergetics*. Supervised by Marko Vendelin and Martin Laasmaa, his work developed a model to estimate diffusion barriers and ATP-synthesis rates in mouse and rat heart cells from experimental measurements.

Kristofer Hiis-Hommuk defended his master's thesis, *Applying RICS for analysis of heterogeneous solutions*. Supervised by Marko Vendelin, his work used fluorescence correlation spectroscopy and raster image correlation spectroscopy to measure lipoprotein lipase diffusion and developed a filtering approach for heterogeneous samples.

We congratulate Cärolin, Celica, Otto, and Kristofer, and wish them every success in their future work.

---

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